Effect of Calcium Silicate-Based Root Canal Medicament After Retreatment

NACompletedINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

June 12, 2024

Primary Completion Date

December 12, 2024

Study Completion Date

January 10, 2025

Conditions
Antibacterial AgentsPostoperative Dental PainAntifungal Agents
Interventions
DRUG

Calcium Silicate

Root canal filling was removed with endodontic file. Sterile paper points were placed at working length to assess antibacterial and antifungal effects before the medicament was placed. Subsequently, the root canals were chemomechanically prepared, final irrigation activation was performed, and second samples were collected in the same manner. The calcium silicate-based root canal medicament was placed in the canals, and the teeth were sealed with temporary fillings. A form was provided to evaluate the patients' postoperative pain levels over one week. At the second appointment, the medicament was removed, and third samples were collected to assess antibacterial effects. The root canal treatments of the patients were completed. The antibacterial and antifungal effects of the medicaments were evaluated using PCR, and the patients' postoperative pain levels were recorded using follow-up forms.

DRUG

Calcium hydroxide

Root canal filling was removed with endodontic file. Sterile paper points were placed at working length to assess antibacterial and antifungal effects before the medicament was placed. Subsequently, the root canals were chemomechanically prepared, final irrigation activation was performed, and second samples were collected in the same manner. The calcium hydroxide-based root canal medicament was placed in the canals, and the teeth were sealed with temporary fillings. A form was provided to evaluate the patients' postoperative pain levels over one week. At the second appointment, the medicament was removed, and third samples were collected to assess antibacterial effects. The root canal treatments of the patients were completed. The antibacterial and antifungal effects of the medicaments were evaluated using PCR, and the patients' postoperative pain levels were recorded using follow-up forms.

Trial Locations (1)

25240

Ataturk University, Erzurum

All Listed Sponsors
lead

Ataturk University

OTHER

NCT06779370 - Effect of Calcium Silicate-Based Root Canal Medicament After Retreatment | Biotech Hunter | Biotech Hunter