20
Participants
Start Date
January 15, 2025
Primary Completion Date
December 1, 2025
Study Completion Date
March 1, 2026
nicotinamide adenine dinucleotid/nicotinamide mononucleotide
"Drug: intravenous nicotinamide adenine dinucleotide (Coenzyme I for Injection) administration This study adopts a prospective, single arm, open design method. Twenty subjects were enrolled in the study and were treated with nicotinamide adenine dinucleotide (100mg/d) for 1 week.~Drug: oral nicotinamide mononucleotide administration This study adopts a prospective, single arm, open design method. Twenty subjects were enrolled in the study and were treated with nicotinamide mononucleotide 450mg BID for 2 weeks.~The first stage is the main research stage (d0-w2), which is the core treatment period. The aim is to observe the safety and efficacy during treatment.~The second stage (w2-w8) is the stage of withdrawal from the visit, mainly to observe the safety and continuous efficacy after treatment."
RECRUITING
Chinese Academy of Medical Science and Blood Disease Hospital, Tianjin
Institute of Hematology & Blood Diseases Hospital, China
OTHER