206
Participants
Start Date
February 28, 2025
Primary Completion Date
September 30, 2027
Study Completion Date
January 31, 2028
CPAP Therapy Combined with Web-Based Sleep Education for Cognitive and Sleep Health
Participants in Group 1 will receive CPAP therapy immediately upon enrollment alongside web-based sleep education through the Brain Health Pro (BHP) platform. The CPAP intervention includes a study-provided auto-titrating device, in-person mask fitting, and ongoing support from a study sleep technologist. Adherence will be monitored via remote data uploads. The BHP platform is a 45-week web-based formal educational program program designed to increase dementia literacy, foster engagement, and convey best available evidence for lifestyle changes that can mitigate dementia risk. This combined approach ensures simultaneous initiation of CPAP and educational reinforcement to optimize adherence and cognitive outcomes.
Delayed CPAP Therapy Combined with Web-Based Sleep Education for Cognitive and Sleep Health
Participants in Group 2 will begin with 4 months of BHP web-based sleep education before adding CPAP therapy for the remaining 4 months. CPAP setup and support are identical to the Early CPAP group. Participants in Group 2 will experience procedure similar to current clinical practices.
Sunnybrook Health Sciences Centre, Toronto
Baycrest
OTHER
University Health Network, Toronto
OTHER
Centre for Addiction and Mental Health
OTHER
Sunnybrook Health Sciences Centre
OTHER