Host Immunity, Plasmodium and Pathogens Co-Infections

NANot yet recruitingINTERVENTIONAL
Enrollment

2,000

Participants

Timeline

Start Date

February 15, 2025

Primary Completion Date

February 15, 2027

Study Completion Date

August 15, 2027

Conditions
MalariaBacterial Co-infection
Interventions
OTHER

Blood sample

For febrile children at the time of inclusion : 6.25 ml to 8.25 ml of blood ; For non febrile children at the time of inclusion : 4 ml of blood ; For pregnant women at the time of inclusion : 5 ml of peripheral blood, 5 ml of placental blood, 20 to 40 ml of umbilical cord blood ; For new borns : drop of blood on child's heel each month and 5 ml of blood the 12th and last month.

OTHER

Urine sample

For febrile children : 10 ml of urine

OTHER

oropharyngeal sample

For febrile children : oropharyngeal swab sampling

OTHER

Optionnal : stool sample

For febrile children (only as part of the care of the child) : 5g stool

OTHER

Optionnal : cerebrospinal fluid

For febrile children (only as part of the care of the child in case of suspected meningitis) : 4 additional drops of cerebrospinal fluid

OTHER

placental biopsy

For pregnant women : placental biopsy the size of 2 rice grains

Sponsors

Lead Sponsor

All Listed Sponsors
collaborator

Institut de Recherche pour le Developpement

OTHER_GOV

lead

Institut Pasteur

INDUSTRY

NCT06769815 - Host Immunity, Plasmodium and Pathogens Co-Infections | Biotech Hunter | Biotech Hunter