A Phase I Study of HY-2003 in the Subjects With Excessive Submental Fat Accumulation

PHASE1RecruitingINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

December 26, 2024

Primary Completion Date

February 5, 2026

Study Completion Date

February 5, 2026

Conditions
Moderate or Severe Submental Fullness
Interventions
DRUG

HY-2003 (10 mg/ml), BELKYRA and placebo

Participants received HY-2003 (10 mg/ml), or BELKYRA, or placebo administered up to 10 mL per treatment session at intervals of approximately 4 weeks for up to a maximum of 6 treatments.

DRUG

HY-2003 (5 mg/ml) and placebo

Participants received HY-2003 (5 mg/ml) or placebo administered up to 10 mL per treatment session at intervals of approximately 2 weeks for up to a maximum of 6 treatments.

DRUG

HY-2003 (5 mg/ml) and placebo

Participants received HY-2003 (10 mg/ml) or placebo administered up to 10 mL per treatment session at intervals of approximately 4 weeks for up to a maximum of 6 treatments. It is possible to explore the maximum number of administrations exceeding six treatment sessions.

Trial Locations (2)

100730

RECRUITING

Peking Union Medical College Hospital, Beijing

710061

RECRUITING

The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an

All Listed Sponsors
collaborator

Peking Union Medical College Hospital

OTHER

collaborator

First Affiliated Hospital Xi'an Jiaotong University

OTHER

lead

Sichuan Huiyu Pharmaceutical Co., Ltd

INDUSTRY