Reinforced Pancreaticojejunostomy With or Without glubran2

PHASE2RecruitingINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

January 15, 2025

Primary Completion Date

January 15, 2026

Study Completion Date

February 15, 2026

Conditions
Pancreatic FistulaPancreas CancerPeriampullary CarcinomaPancreatic Ductal Adenocarcinoma
Interventions
DRUG

Reinforced pancreaticojejunostomy with tissue adhesive glue modified cyanoacrylate (glubran 2)

pancreaticojejunostomy was done with application of glubran 2: The blister pack was opened, and the sterile single-dose vial was released directly onto the operating table in a sterile environment, Draw the Glubran 2 out of the single-dose vial using a sterile syringe then put the syringe into applicator Glubran 2 was applied into anastomosis by applicator in spraying manner . Whenever possible, the area to be treated should be cleaned before application. When applied in such a minimal amount, once it had polymerized, Glubran 2 formed a thin adhesive layer. It was therefore essential not to apply more than one drop in the same point. A second layer of Glubran 2 may not be applied until the first had polymerized. Any excess product was removed using a dry swab within 5-6 seconds after application. Glubran 2 was not touched after application until the polymerization reaction is complete, as it may detach or not produce the desired effect.

PROCEDURE

Pancreaticojejunostomy without tissue adhesive glue modified cyanoacrylate (glubran 2)

Pancreaticojejunostomy without tissue adhesive glue modified cyanoacrylate (glubran 2)

Trial Locations (1)

61519

RECRUITING

Liver and GIT hospital / Minia university, Minya

All Listed Sponsors
lead

Minia University

OTHER