88
Participants
Start Date
January 15, 2025
Primary Completion Date
November 1, 2027
Study Completion Date
August 31, 2029
Prednisone + Jakavi(ruxolitinib)
"The experimental group will receive ruxolitinib 10 mg orally twice daily (BID) and prednisone (or equivalent) at a dosage of 1 mg/kg/day.~Subjects are orally administered with an investigational medicinal product (IMP) according to their designated treatment group for 48 weeks, and the investigator may adjust the dosage of IMPs based on symptoms of the target disease. (However, after the 48-week mark, participants in the ruxolitinib treatment group may continue to receive ruxolitinib for an additional maximum of 2 years, based on the investigator's judgment regarding the need for ongoing treatment. The total duration of ruxolitinib administration will not exceed 3 years.)"
Prednisone
"The control group will receive prednisone (or equivalent) at a dosage of 1 mg/kg/day.~Subjects are orally administered with an investigational medicinal product (IMP) according to their designated treatment group for 48 weeks, and the investigator may adjust the dosage of IMPs based on symptoms of the target disease."
RECRUITING
The Catholic University of Korea, Seoul St. Mary's Hospital, Seoul
Collaborators (1)
Novartis
INDUSTRY
Byung-Sik Cho
OTHER