Dapagliflozin Versus Dexamethasone Role in Pre-operative Management of Non- Diabetic Brain Tumor Patients

PHASE3Not yet recruitingINTERVENTIONAL
Enrollment

75

Participants

Timeline

Start Date

August 20, 2025

Primary Completion Date

October 20, 2026

Study Completion Date

December 20, 2026

Conditions
GliomaDapagliflozin (Forxiga)Dexamethasone
Interventions
DRUG

Dapagliflozin placebo

Twenty-five non-diabetic glioma patients on levetiracetam, and not on SGLT2 inhibitors will receive Dapagliflozin 10 mg once daily for 14 days pre-operative

DRUG

Placebo

Twenty-five non-diabetic glioma patients on levetiracetam, and not on SGLT2 inhibitors will receive placebo tablets once daily for 14 days pre-operative.

DRUG

DexamethasoneGroup III (n=25) (Dexamethasone group)

Twenty-five non-diabetic glioma patients on levetiracetam, and not on SGLT2 inhibitors will receive Dexamethasone 8 mg tablets once daily for 14 days pre-operative.

All Listed Sponsors
lead

Tanta University

OTHER