GRAViceptive NEGlect Treatment in Acute Stroke Using Targeted Cranial ELECTrotherapy

PHASE1/PHASE2RecruitingINTERVENTIONAL
Enrollment

28

Participants

Timeline

Start Date

January 3, 2025

Primary Completion Date

January 15, 2026

Study Completion Date

January 15, 2026

Conditions
Stroke
Interventions
DEVICE

Active: High-Definition transcranial Direct Current Stimulation (HD-tDCS)

Active high-definition transcranial direct current stimulation (HD-tDCS) will be delivered by a low-intensity direct current stimulator (Soterix Medical) using a 3x1 ring configuration with a central cathode over the contralesional temporo-parietal junction. During the stimulation, participants will perform tasks to stimulate correct visual verticality perception. Six active HD-tDCS sessions of 2mA for 20 minutes HD-tDCS, 3 times daily for 2 days with session intervals greater than 3 hours.

DEVICE

Sham: High-Definition transcranial Direct Current Stimulation (HD-tDCS)

Six sessions (3 times daily for 2 days) of 2mA sham HD-tDCS cathode center over the contralesional TPJ for 20min. Direct current (DC) will be generated by a low-intensity direct current stimulator (Soterix Medical) and then split into the 3 high-density Ag/AgCl sintered ring electrodes. The sham stimulation condition will consist of the same positioning of the electrodes as the active condition, with a ramp-up to 2mA over 30 seconds and a subsequent ramp-down of 30 seconds.

Trial Locations (2)

14015160

RECRUITING

Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto

14049-900

NOT_YET_RECRUITING

University of São Paulo, Ribeirão Preto Medical School, Ribeirão Preto

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Thomas Jefferson University

OTHER

collaborator

Fundação de Amparo à Pesquisa do Estado de São Paulo

OTHER_GOV

collaborator

Viasonix

UNKNOWN

collaborator

Phelcom

UNKNOWN

collaborator

FBX Medical

UNKNOWN

lead

University of Sao Paulo

OTHER

NCT06747676 - GRAViceptive NEGlect Treatment in Acute Stroke Using Targeted Cranial ELECTrotherapy | Biotech Hunter | Biotech Hunter