Study on the Treatment of Hepatitis B Virus(HBV) Infected Individuals With Peginterferon α-2b Combined With NA.

RecruitingOBSERVATIONAL
Enrollment

400

Participants

Timeline

Start Date

May 25, 2023

Primary Completion Date

May 25, 2027

Study Completion Date

May 25, 2029

Conditions
HBV
Interventions
DRUG

Peg-IFNα-2b combined with NA

From baseline day 1, take NA orally once daily until the drug can be discontinued. Concurrently, combine with Peg-IFN α-2b 180μg, administered subcutaneously once a week for 48-96 weeks (if the surface antigen is not converted to negative at week 48, continue Peg-IFN α-2b treatment, but the course of treatment should not exceed 96 weeks). Discontinue Peg-IFN α-2b (while maintaining continuous oral administration of NA), and continue taking NA orally.

DRUG

Nucleotide Analogues

Starting from the first day of enrollment, take NA orally once a day.

Trial Locations (4)

Unknown

RECRUITING

The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou

RECRUITING

Chenzhou Second People's Hospital, Chenzhou

RECRUITING

First Affiliated Hospital of Nanhua University, Hengyang

RECRUITING

Hengyang Third People's Hospital, Hengyang

All Listed Sponsors
lead

Xiangya Hospital of Central South University

OTHER