NCT06743555View on ClinicalTrials.gov

Surgery After Verifying Existing Disease in Locally Advanced Operable Lung Cancer: A Pilot Study

PHASE1Not yet recruitingINTERVENTIONAL
Enrollment

14

Participants

Timeline

Start Date

February 28, 2025

Primary Completion Date

February 28, 2027

Study Completion Date

February 29, 2032

Conditions
Non-Small Cell Lung CancerImmunotherapyNeoadjuvant TherapyThoracic SurgeryComplete Response
Interventions
OTHER

Observation without surgery

Patients randomized to this arm will forego standard-of-care thoracic surgery and will undergo strict surveillance based on serial radiological follow-up and ctDNA monitoring

PROCEDURE

Standard-of-care surgery

Patients randomized to this arm will undergo standard-of-care thoracic surgery and undergo post-operative surveillance with serial radiological follow-up and ctDNA monitoring

Trial Locations (1)

H2X 3E4

Centre hospitalier de l'Université de Montréal (CHUM), Montreal

All Listed Sponsors
lead

Centre hospitalier de l'Université de Montréal (CHUM)

OTHER