Hypoxic Red Blood Cells in Sickle Cell Anemia

NANot yet recruitingINTERVENTIONAL
Enrollment

48

Participants

Timeline

Start Date

January 31, 2026

Primary Completion Date

February 29, 2028

Study Completion Date

June 30, 2028

Conditions
Sickle Cell AnaemiaSickle Cell Anemia CrisisSickle Cell Anemia in ChildrenSickle Cell Anemia (HbSS, or HbSβ-thalassemia0)
Interventions
DEVICE

Hemanext ONE System

Hypoxic red blood cells

DEVICE

Conventional RBCs

Conventional red blood cells

Trial Locations (6)

15213

University of Pittsburgh, Pittsburgh

15260

University of Pittsburgh Medical Center, Pittsburgh

21287

John Hopkins University School of Medicine, Baltimore

30322

Emory University School of Medicine, Atlanta

33701

Johns Hopkins All Children's Hospital, St. Petersburg

06030

New England Sickle Cell Institute, University of Connecticut, Farmington

Sponsors

Lead Sponsor

All Listed Sponsors
collaborator

Emory University

OTHER

collaborator

University of Connecticut

OTHER

collaborator

University of Pittsburgh Medical Center

OTHER

collaborator

Johns Hopkins All Children's Hospital

OTHER

collaborator

Johns Hopkins University

OTHER

lead

Hemanext

INDUSTRY

NCT06743113 - Hypoxic Red Blood Cells in Sickle Cell Anemia | Biotech Hunter | Biotech Hunter