NCT06740214View on ClinicalTrials.gov

Analgesic Efficacy of Different Liposomal Bupivacaine Doses in the Adductor Canal Block for Total Knee Arthroplasty

PHASE3Not yet recruitingINTERVENTIONAL
Enrollment

177

Participants

Timeline

Start Date

July 1, 2025

Primary Completion Date

June 30, 2027

Study Completion Date

June 30, 2028

Conditions
Pain, PostoperativeAnalgesic EffectTotal Knee ArthroplastyLiposomal BupivacaineDose Response Relationship, Drug
Interventions
DRUG

0.5% standard bupivacaine only

20ml 0.5% standard bupivacaine only

DRUG

1.33% liposomal bupivacaine with 0.5% standard bupivacaine

10ml 1.33% liposomal bupivacaine (133mg) plus 10ml 0.5% standard bupivacaine

DRUG

1.33% liposomal bupivacaine only

20ml 1.33% liposomal bupivacaine (266mg)

Trial Locations (1)

Unknown

The University of Hong Kong, Hong Kong

All Listed Sponsors
lead

The University of Hong Kong

OTHER