Evaluation of Hydrogel Application in the Treatment of Periodontitis and Peri-implantitis

NAActive, not recruitingINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

June 1, 2024

Primary Completion Date

January 1, 2026

Study Completion Date

March 1, 2026

Conditions
Periodontal Disease Stage 2Peri-Implantitis and Peri-implant MucositisPeriodontal Regeneration
Interventions
PROCEDURE

Nonsurgical periodontal treatment and application of H42® hydrogel to the peri-implant pocket

Firstly, after appropriate oral hygiene training, full mouth supragingival scaling will be performed using an ultrasonic device (EMS Piezon ultrasonic system, EMS Electro Medical Systems, Switzerland). Non-surgical periodontal treatment will be completed after subgingival curettage of peri-implant pocket areas between 5-8 mm in the contralateral quadrant. The tested site will be partially isolated and then air-dried. A bent, blunt-tipped needle syringe will be used to inject the H42® hydrogel into the pocket, ensuring that the tip reaches the deepest point of the pocket. Once the gel is visible at the gingival margin, the needle will be gently removed from the pocket. After approximately 0.1 mL of gel has been applied, excess gel will be removed with a sterile gauze swab to prevent any spreading effect or possible systemic effect. After application of the H42 hydrogel, the area will be kept dry for 5 minutes to ensure optimum adhesion of H42 to the pocket tissue.

PROCEDURE

Nonsurgical periodontal treatment of periodontal pocket

Systemic and dental anamnesis will be taken from all patients. Firstly, after appropriate oral hygiene education, full mouth supragingival scaling will be performed using an ultrasonic device (EMS Piezon ultrasonic system, EMS Electro Medical Systems, Switzerland). Non-surgical periodontal treatment will be completed after subgingival curettage of periodontal pocket areas between 5-8 mm in the contralateral quadrant.

PROCEDURE

Non-surgical periodontal treatment and application of H42® hydrogel to the periodontal pocket

Firstly, after appropriate oral hygiene training, full mouth supragingival scaling will be performed using an ultrasonic device (EMS Piezon ultrasonic system, EMS Electro Medical Systems, Switzerland). Non-surgical periodontal treatment will be completed after subgingival curettage of periodontal pocket areas between 5-8 mm in the contralateral quadrant. The tested site will be partially isolated and then air-dried. A bent, blunt-tipped needle syringe will be used to inject the H42® hydrogel into the pocket, ensuring that the tip reaches the deepest point of the pocket. Once the gel is visible at the gingival margin, the needle will be gently removed from the pocket. After approximately 0.1 mL of gel has been applied, excess gel will be removed with a sterile gauze swab to prevent any spreading effect or possible systemic effect. After application of the H42 hydrogel, the area will be kept dry for 5 minutes to ensure optimum adhesion of H42 to the pocket tissue.

PROCEDURE

Nonsurgical periodontal treatment of peri-implant pocket

Systemic and dental anamnesis will be taken from all patients. Firstly, after appropriate oral hygiene education, full mouth supragingival scaling will be performed using an ultrasonic device (EMS Piezon ultrasonic system, EMS Electro Medical Systems, Switzerland). Non-surgical periodontal treatment will be completed after subgingival curettage of peri-implant pocket areas between 5-8 mm in the contralateral quadrant.

Trial Locations (1)

43100

Kütahya Health Sciences University Faculty of Dentistry, Kütahya

All Listed Sponsors
lead

Kutahya Health Sciences University

OTHER

NCT06740123 - Evaluation of Hydrogel Application in the Treatment of Periodontitis and Peri-implantitis | Biotech Hunter | Biotech Hunter