NCT06738017View on ClinicalTrials.gov

Study of BMN 349 Single Dose in PiZZ and PiMZ/MASH Adult Participants

PHASE1RecruitingINTERVENTIONAL
Enrollment

12

Participants

Timeline

Start Date

February 21, 2025

Primary Completion Date

September 30, 2025

Study Completion Date

September 30, 2025

Conditions
Alpha 1-Antitrypsin Deficiency
Interventions
DRUG

BMN 349

250mg oral tablet

DRUG

Placebo

250mg oral tablet

Trial Locations (8)

29425

RECRUITING

The Medical University of South Carolina, Charleston

45227

RECRUITING

Medpace Clinical Pharmacology Unit, Cincinnati

63110

RECRUITING

Saint Louis University, St Louis

92037

RECRUITING

University of California, San Diego, San Diego

Unknown

RECRUITING

NHS Lothian, Edinburgh

RECRUITING

Royal Free London NHS Foundation Trust, London

NOT_YET_RECRUITING

Nottingham University Hospitals, Nottingham

RECRUITING

University Hospital Southampton NHS Foundation Trust, Southampton

Sponsors
All Listed Sponsors
lead

BioMarin Pharmaceutical

INDUSTRY