NB02 (Poseltinib) Combined Rituximab and Lenalidomide in R/R PCNSL

PHASE2RecruitingINTERVENTIONAL
Enrollment

33

Participants

Timeline

Start Date

November 25, 2024

Primary Completion Date

June 30, 2026

Study Completion Date

December 31, 2027

Conditions
Primary CNS Lymphoma (PCNSL)
Interventions
DRUG

R2P -> RP

"Induction(R2P) 21 days per cycles, 6 cycles~* NB02 : 60mg BID PO, Day 1-21~* Rituximab 375mg/m2 DAY IV Day 1, 8, 15 at 1st cycle; D1 at 2nd to 6th cycles~* Lenalidomide : 20mg QD PO, Day 1-14~Maintenance(RP) 21 days per cycles, until Progression~* NB02 : 60mg BID PO, Day 1-21~* Lenalidomide : 20mg QD PO, Day 1-14"

Trial Locations (10)

Unknown

NOT_YET_RECRUITING

Kosin University Gospel Hospital, Busan

NOT_YET_RECRUITING

Chonnam National University Hwasun Hospital, Hwasun

NOT_YET_RECRUITING

Korea National Cancer Center, Ilsan

NOT_YET_RECRUITING

Seoul National University Bundang Hospital, Seongnam

NOT_YET_RECRUITING

Asan Medical Center, Seoul

NOT_YET_RECRUITING

Catholic univ of Yeouido St Mary's Hospital, Seoul

NOT_YET_RECRUITING

Korea University Anam Hospital, Seoul

NOT_YET_RECRUITING

Samsung Medical Center, Seoul

RECRUITING

Seoul National University Hospital, Seoul

NOT_YET_RECRUITING

Ulsan University Hospital, Ulsan

Sponsors

Lead Sponsor

All Listed Sponsors
lead

NOBO Medicine

INDUSTRY

NCT06737250 - NB02 (Poseltinib) Combined Rituximab and Lenalidomide in R/R PCNSL | Biotech Hunter | Biotech Hunter