Ketogenic Diets for Weight Loss Maintenance: Impact on Energy Expenditure and Appetite in Individuals With Obesity

NARecruitingINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

August 1, 2025

Primary Completion Date

December 31, 2025

Study Completion Date

March 31, 2026

Conditions
Obesity
Interventions
BEHAVIORAL

Diet Therapy

Participants will be provided food to meet the ketogenic diet prescription for the 6-week weight maintenance phase.

BEHAVIORAL

Calorie Restriction

Participants will follow a commercial low-energy diet and be provided with meal replacements for 4 weeks aiming to achieve a minimum of 5% weight loss.

BEHAVIORAL

Behavioral Support

Participants will meet weekly with a registered dietitian, for a 20-minute consultation throughout the entire study period (10 weeks) to increase engagement and improve adherence and retention.

BEHAVIORAL

Diet Therapy

Participants will have food provided to meet the standard low-fat diet prescription for the 6-week weight maintenance phase.

Trial Locations (1)

35294

RECRUITING

University of Alabama at Birmingham, Birmingham

All Listed Sponsors
collaborator

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NIH

lead

University of Alabama at Birmingham

OTHER

NCT06736028 - Ketogenic Diets for Weight Loss Maintenance: Impact on Energy Expenditure and Appetite in Individuals With Obesity | Biotech Hunter | Biotech Hunter