Clinical Outcomes of Sutured Versus Sutureless Conjunctival Autograft in Primary Pterygium Excision

NANot yet recruitingINTERVENTIONAL
Enrollment

70

Participants

Timeline

Start Date

December 15, 2024

Primary Completion Date

April 20, 2025

Study Completion Date

September 1, 2025

Conditions
Pterygium of Conjunctiva and CorneaPterygium of Both EyesPterygium
Interventions
PROCEDURE

Clinical outcomes of sutured versus sutureless conjunctival autograft in primary pterygium excision

Studies have concluded that pterygium surgical excision is the main treatment for pterygium. Pterygium excision with superior graft is the procedure followed most commonly at present. This is achieved by many methods, with the result differing from one method to another. The most important difference is the incidence of recurrence(4)But Varioustechniques such as Bare Sclera, Rotational Conjunctival Flap, Limbal Conjunctival Autograft, Amniotic Membrane Graft, and Free Conjunctival Autograft are also used for the removal of pterygium(3 ,4)Of the various possible alternative approaches, conjunctival autograft is usually preferred. Diverse methods for grafting with sutures, glue or autologous serum from the recipient bed are in use (5,6). Many adjunctive therapies like mitomycin C, corticosteroids, thiotepa, interferon-alpha- 2b, beta irradiation, 5-FU are being used to decrease the risk of recurrence after surgical removal of pterygium.

PROCEDURE

pterygium excision and conjuctival graft suturing

pterygium is surgically removed, and a conjuctival graft is placed on bare sclera using sutures to surrounding conjuctiva.

PROCEDURE

pterygium excision and conjuctival graft placement by autologous blood

pterygium is surgically removed and a conjuctival graft is placed on bare sclera on which the patient's blood remains. the graft is left without sutures, adhering only by autologous blood.

Trial Locations (2)

Unknown

Ophthalmology department Assiut university, Asyut

Ophthalmology department, Assiut University hospital, Asyut

All Listed Sponsors
lead

Assiut University

OTHER

NCT06734663 - Clinical Outcomes of Sutured Versus Sutureless Conjunctival Autograft in Primary Pterygium Excision | Biotech Hunter | Biotech Hunter