Randomized Control Trial of Sleeve Gastrectomy with Tirzepatide in Maximizing Weight Loss

In this study, the intervention group (n=21) are patients who will undergo sleeve gastrectomy and receive tirzepatide after surgery. Patients who were selected in this arm will undergo a 4-week dose escalation period. Starting at 6 months they will receive weekly 2.5mg doses (for 4 weeks). Afterwards, they will receive weekly 5mg doses. They will maintain this dose until 12 months after surgery.

Subjects in both the interventional group (n=21) and the control group (n=21) will undergo sleeve gastrectomy.