Best Hypnotic Drug Choice for Rapid Sequence Induction in the Operating Room

PHASE3RecruitingINTERVENTIONAL
Enrollment

1,218

Participants

Timeline

Start Date

April 14, 2025

Primary Completion Date

April 14, 2027

Study Completion Date

April 30, 2027

Conditions
Rapid Sequence Induction
Interventions
DRUG

direct IV injection

direct IV injection at dosage of 2 mg/kg (adjusted body weight if BMI \> 30) after completing pre-oxygenation

DRUG

combination of Ketamine and Propofol

combination of Ketamine and Propofol described above: consecutive direct IV injection of Ketamine 1 mg/kg and Propofol 1 mg/kg (adjusted body weight if BMI \> 30). Dilution are not necessary.

Trial Locations (20)

44093

NOT_YET_RECRUITING

Chu Nantes (Laennec), Nantes

RECRUITING

Chu Nantes, Nantes

Unknown

RECRUITING

Chr Angers, Angers

NOT_YET_RECRUITING

CHRU de Brest Hôpital Cavale Blanche, Brest

NOT_YET_RECRUITING

Ch Louis Pasteur, Chartres

NOT_YET_RECRUITING

CHU Dijon, Dijon

NOT_YET_RECRUITING

CHU Grenoble Alpes, Grenoble

RECRUITING

CHD Vendée, La Roche-sur-Yon

NOT_YET_RECRUITING

APHP Bicêtre, Le Kremlin-Bicêtre

RECRUITING

CH Le Mans, Le Mans

RECRUITING

CHU Lille Hopital Salengro, Lille

RECRUITING

CHU Lille Hôpital Claude Huriez, Lille

NOT_YET_RECRUITING

CHU Lyon Hôpital Sud, Lyon

NOT_YET_RECRUITING

HCL Lyon Croix-Rousse, Lyon

NOT_YET_RECRUITING

APHP St-Antoine, Paris

NOT_YET_RECRUITING

APHP Tenon, Paris

NOT_YET_RECRUITING

CHU Poitiers, Poitiers

NOT_YET_RECRUITING

Hopital Foch, Suresnes

NOT_YET_RECRUITING

CHU Toulouse Hôpital Purpan, Toulouse

NOT_YET_RECRUITING

CHU Toulouse Hôpital Rangueil, Toulouse

All Listed Sponsors
lead

Nantes University Hospital

OTHER