Protective Effect of PCSK9 Inhibitor Against Negative Inflammatory Response and Organ Dysfunction After Coronary Artery Bypass Grafting (PANDA VIII)

NANot yet recruitingINTERVENTIONAL
Enrollment

400

Participants

Timeline

Start Date

January 1, 2025

Primary Completion Date

December 31, 2026

Study Completion Date

December 31, 2026

Conditions
Myocardial Ischaemic SyndromeCoronary Heart Disease
Interventions
DRUG

PCSK9 inhibitor

the experiment group will receive first PCSK9 inhibitor before CABG, then twice a month until 3 months later.

DRUG

Statin

the control group will receive standard statin therapy.

Trial Locations (2)

210029

The First Affiliated Hospital of Nanjing Medical University, Nanjing

Unknown

Beijing Anzhen Hospital, Capital Medical University, Beijing

Sponsors
All Listed Sponsors
collaborator

The First Affiliated Hospital with Nanjing Medical University

OTHER

collaborator

Beijing Anzhen Hospital

OTHER

lead

Nanjing Medical University

OTHER