NCT06729970View on ClinicalTrials.gov

A Study to Evaluate the Effects of Lithium, Valproic Acid, and Lamotrigine on the Pharmacokinetics of KarXT and Effects of KarXT on the Pharmacokinetics of Lithium, Valproic Acid, and Lamotrigine in Healthy Participants

PHASE1RecruitingINTERVENTIONAL
Enrollment

130

Participants

Timeline

Start Date

December 26, 2024

Primary Completion Date

January 18, 2026

Study Completion Date

January 18, 2026

Conditions
Healthy Volunteers
Interventions
DRUG

Xanomeline/Trospium Chloride

Specified dose on specified days

DRUG

Lithium

Specified dose on specified days

DRUG

Valproic Acid

Specified dose on specified days

DRUG

Lamotrigine

Specified dose on specified days

Trial Locations (1)

90720-3115

RECRUITING

CenExel Collaborative Neuroscience Research, LLC - Los Alamitos, Los Alamitos

Sponsors
All Listed Sponsors
lead

Karuna Therapeutics

INDUSTRY

NCT06729970 - A Study to Evaluate the Effects of Lithium, Valproic Acid, and Lamotrigine on the Pharmacokinetics of KarXT and Effects of KarXT on the Pharmacokinetics of Lithium, Valproic Acid, and Lamotrigine in Healthy Participants | Biotech Hunter | Biotech Hunter