Phase II Clinical Study of AC591 in Preventing Oxaliplatin-Induced Peripheral Neuropathy

PHASE2Not yet recruitingINTERVENTIONAL
Enrollment

120

Participants

Timeline

Start Date

December 31, 2024

Primary Completion Date

December 31, 2026

Study Completion Date

December 31, 2026

Conditions
Colorectal Adenoma
Interventions
DRUG

CAPEOX

CAPEOX: 130mg/m2 of oxaliplatin (D1, central intravenous drip for 2h (time window + 20min)), 1000mg/m2 of capecitabine tablets each time, orally, twice a day (D1-D14, morning and evening); repeat the CAPEOX chemotherapy regimen every 3 weeks.

DRUG

Placebo

Placebo:3 times a day (daily), taken with boiled water.

DRUG

AC591

AC591 : 3 times a day (daily), taken with boiled water.

All Listed Sponsors
lead

Shandong New Time Pharmaceutical Co., LTD

INDUSTRY