Study of Adjuvant Nimotuzumab Combined with Nab-paclitaxel+ Gemcitabine in EGFR-positive Pancreatic Cancer

PHASE2RecruitingINTERVENTIONAL
Enrollment

57

Participants

Timeline

Start Date

November 15, 2024

Primary Completion Date

September 30, 2028

Study Completion Date

September 30, 2028

Conditions
Pancreatic Cancer Resectable
Interventions
DRUG

Nimotuzumab

Nimotuzumab 400 mg on Day 1 and 15 of a 28-day cycle (6 cycles) ; Patients will receive Nimotuzumab 600 mg on days 1 and 8 of every 21-day cycle. Patients will receive six treatment cycles unless there is radiologic evidence of disease recurrence and unacceptable toxicity.

DRUG

AG

Patients will receive nab-paclitaxel 125 mg/m\^2 followed by gemcitabine 1,000 mg/m\^2 as one intravenous infusion over 30-40 minutes on days 1 and 8 of every 21-day cycle. Patients will receive six treatment cycles unless there is radiologic evidence of disease recurrence and unacceptable toxicity.

Trial Locations (1)

Unknown

RECRUITING

Zhejiang Provincial People's Hospital, Hangzhou

All Listed Sponsors
lead

Zhejiang Provincial People's Hospital

OTHER