12
Participants
Start Date
March 1, 2025
Primary Completion Date
December 31, 2025
Study Completion Date
February 1, 2026
Continuous intravenous stable isotope amino acid tracer infusion
During the single 12 h trial day, a primed continuous stable isotope infusion will run in order to assess muscle protein synthesis in the basal (4 h) and post-prandial (8 h) state.
Amino acid infusion
In order to assess muscle protein synthesis rates during continuous elevated plasma amino acid availability, the amino acid infusion solution Vamin®14 EF will be used. Vamin® 14EF contains 85g amino acids per liter and will be administered in the post-prandial period for 8 hours to ensure a constant rate of amino acid infusion over the full assessment period of the primary outcome measure.
Maastricht University Medical Centre+, Maastricht
Maastricht University Medical Center
OTHER