Re-evaluation of the Muscle-full Effect During Continuously Elevated Amino Acid Availability in Healthy Young Males

NANot yet recruitingINTERVENTIONAL
Enrollment

12

Participants

Timeline

Start Date

March 1, 2025

Primary Completion Date

December 31, 2025

Study Completion Date

February 1, 2026

Conditions
Muscle Protein Synthesis
Interventions
OTHER

Continuous intravenous stable isotope amino acid tracer infusion

During the single 12 h trial day, a primed continuous stable isotope infusion will run in order to assess muscle protein synthesis in the basal (4 h) and post-prandial (8 h) state.

OTHER

Amino acid infusion

In order to assess muscle protein synthesis rates during continuous elevated plasma amino acid availability, the amino acid infusion solution Vamin®14 EF will be used. Vamin® 14EF contains 85g amino acids per liter and will be administered in the post-prandial period for 8 hours to ensure a constant rate of amino acid infusion over the full assessment period of the primary outcome measure.

Trial Locations (1)

6229ER

Maastricht University Medical Centre+, Maastricht

All Listed Sponsors
lead

Maastricht University Medical Center

OTHER

NCT06721026 - Re-evaluation of the Muscle-full Effect During Continuously Elevated Amino Acid Availability in Healthy Young Males | Biotech Hunter | Biotech Hunter