The Microbial Impact on Intestinal Fibrosis and the Associated Immune Microenvironment in Crohn's Disease

Not yet recruitingOBSERVATIONAL
Enrollment

20

Participants

Timeline

Start Date

April 30, 2025

Primary Completion Date

January 31, 2026

Study Completion Date

January 31, 2027

Conditions
Crohn Disease (CD)
Interventions
PROCEDURE

Collection of surgical specimen

Specimens of CD patients and non-IBD related patients will be collected during the surgery performed for clinical practice, without other risks for the patients, since we will use only leftover material after pathologist analysis. All of the collected surgical samples will be used for this project and, for this reason, they will not be conserved after the research period. Any residual samples will be destroyed.

PROCEDURE

Collection of stool sample

One week before the surgery to remove the stricture, fecal samples from CD patients belonging to B1, B2, B3 groups will be collected. They will be used for the exploratory objective. All of the collected fecal samples will be used for this project and, for this reason, they will not be conserved after the research period. Any residual samples will be destroyed.

Trial Locations (1)

20132

IRCCS San Raffaele, Milan

All Listed Sponsors
collaborator

University of Florence

OTHER

collaborator

Humanitas Research Hospital IRCCS, Rozzano-Milan

OTHER

collaborator

Ministero dell'Istruzione, dell'Università e della Ricerca

UNKNOWN

collaborator

Università Vita-Salute San Raffaele (MI)

UNKNOWN

lead

IRCCS San Raffaele

OTHER

NCT06720961 - The Microbial Impact on Intestinal Fibrosis and the Associated Immune Microenvironment in Crohn's Disease | Biotech Hunter | Biotech Hunter