DeMONSTRATE-TB Study in Ethiopia

PHASE2/PHASE3RecruitingINTERVENTIONAL
Enrollment

131,438

Participants

Timeline

Start Date

February 27, 2023

Primary Completion Date

January 1, 2025

Study Completion Date

January 1, 2025

Conditions
Reducing Tuberculosis Incidence
Interventions
COMBINATION_PRODUCT

Enhanced community-wide TB intervention

"Interventions in the intervention arms consist of the following key components:~1. an optimized national recommended set of interventions; such as the implementation of all types of contact investigation, targeted TB screening and diagnosis at key affected population, and optimized HIV screening and TPT for PLHIV;~2. intensive, active, and community-based HH screening and diagnosis of TB using combined TB screening (clinical and X-ray) and X-pert MTB/RIF, as indicated;~3. community-based enhanced TPT; and~4. community-based awareness creation and health education using the community social associations."

COMBINATION_PRODUCT

Routine TB program activities

In the control arm, the standard of care will continue per the national guideline.

Trial Locations (2)

Unknown

RECRUITING

Gedebe Hassassa woreda, West Arsi Zone

RECRUITING

Boloso Bombe woreda, Wolayita Zone

All Listed Sponsors
collaborator

KNCV Tuberculosis Foundation

OTHER

lead

Management Sciences for Health

OTHER