A Study of CSCJC3456 in Patients With Advanced Malignant Tumors

PHASE1RecruitingINTERVENTIONAL
Enrollment

102

Participants

Timeline

Start Date

February 13, 2025

Primary Completion Date

June 30, 2027

Study Completion Date

June 30, 2028

Conditions
Advanced Malignant Solid Tumors
Interventions
DRUG

CSCJC3456 tablet

"* Phase Ia: Single and Multiple Dose Escalation.~ 1. Dosage form: tablet.~ 2. Dosage: 7 dose groups, 5 mg, 15 mg, 30 mg, 45 mg, 60 mg, 80 mg, 100 mg.~ 3. Frequency: once daily (tentative), or twice daily and other options (adjusted based on the results of the preliminary trials).~ 4. Duration: 5 mg(days 1-28; 28 days per cycle), other groups (days 1-14; 21 days per cycle) .~* Phase Ib: Cohort Expansion. Dosage and dosing regimen: according to the recommended dosage and dosing cycle from the Phase Ia study."

Trial Locations (1)

100021

RECRUITING

Cancer Hospital Chinese Academy of Medical Sciences, Beijing

All Listed Sponsors
lead

Changshan ConjuChem BioPharmaceutical Research and Development (Hebei) Co., Ltd.

INDUSTRY

NCT06717750 - A Study of CSCJC3456 in Patients With Advanced Malignant Tumors | Biotech Hunter | Biotech Hunter