A Phase I Trial of Tumor-Associated Lymph Node T-Cell Injection With Advanced Malignant Solid Tumors

PHASE1RecruitingINTERVENTIONAL
Enrollment

32

Participants

Timeline

Start Date

February 13, 2025

Primary Completion Date

December 19, 2026

Study Completion Date

December 19, 2027

Conditions
Tumor Associated Lymph Node T CellAdvanced Solid TumorImmunotherapySerplulimab Injection
Interventions
BIOLOGICAL

Tumor Associated Lymph node T cell

At least one lymph sample is resected from each participant, then it is separated and cultured ex vivo to expand the population of Tumor Associated Lymph node T cells . After lymphodepletion, patients are infused with TAL-T.

DRUG

Serplulimab Injection

Srulizumab injection was given intravenous infusion both before and after the TAL-T cells infusion.

Trial Locations (1)

510700

RECRUITING

Sun Yat-sen University Cancer Center, Guangzhou

All Listed Sponsors
collaborator

Sun Yat-sen University

OTHER

lead

Guangzhou FineImmune Biotechnology Co., LTD.

INDUSTRY