Effect of Dexmedetomidine on Hemodynamic Response to Endotracheal Intubation in Hypertensive Patients

PHASE1/PHASE2RecruitingINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

June 22, 2024

Primary Completion Date

November 22, 2024

Study Completion Date

December 1, 2024

Conditions
Elective Surgical PatientHypertensive PatientsBlood PressureHypertensive Elderly PatientsAnxiolytic
Interventions
DRUG

Dexmedetomidine Group / Group D

In this study, the intervention involve administrating 0.5 mcg/kg of Inj dexmedetomidine intravenously over 10 min to patients in intervention group/group D 2 minutes prior to Endotracheal intubation using laryngoscopy aiming to asses its efficacy in attenuating the pressor response to laryngoscopy.

OTHER

Normal Saline (Placebo)

The Placebo group / group C will be administer Normal Saline without any active medication over 10 min to patients, 2 minutes prior to Endotracheal intubation using laryngoscopy to compare its effect to those of Dexmedetomidine in attenuating the pressor response to laryngoscopy.

Trial Locations (1)

Unknown

RECRUITING

Liaquat National Hospital and Medical College, Karachi

All Listed Sponsors
lead

Liaquat National Hospital & Medical College

OTHER