A Dose-Response Controlled Trial of Bevifibatide for Acute Ischemic Stroke

PHASE2RecruitingINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

February 10, 2025

Primary Completion Date

September 1, 2025

Study Completion Date

December 1, 2025

Conditions
Ischemic Stroke, AcuteIschemic StrokeCerebral InfarctionBrain Diseases
Interventions
DRUG

Bevifibatide citrate injection

Bevifibatide citrate injection should be diluted with 0.9% NaCl solution. After the completion of the study drug infusion, if a follow-up cranial NCCT/MRI within 48 hours shows no significant intracranial hemorrhage, all patients will be administered enteric-coated aspirin tablets (100mg, qd) and clopidogrel hydrogen sulfate tablets (75mg, qd) until day 90. All patients will be managed in accordance with the current guidelines for stroke management. The use of low molecular weight heparin for the prevention of deep vein thrombosis is permitted.

Trial Locations (1)

510280

RECRUITING

Zhujiang Hospital of Southern Medical University, Guangzhou

All Listed Sponsors
lead

Zhujiang Hospital

OTHER