Afatinib Combined With Chemotherapy as Conversion Therapy in Unresectable EGFR Sensitive Mutation-positive Stage III NSCLC

PHASE2RecruitingINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

May 1, 2025

Primary Completion Date

May 31, 2026

Study Completion Date

December 31, 2027

Conditions
Carcinoma, Non-Small-Cell Lung
Interventions
DRUG

Afatinib plus chemotherapy as conversion treatment

Patients with unresectable EGFR sensitive mutation-positive stage III NSCLC will receive 3-4 cycles of afatinib plus chemotherapy as the conversion treatment, and then surgery will be provided for patients who are suitable for primary tumor resection.

Trial Locations (1)

250000

RECRUITING

Shandong Public Health Clinical Center, Jinan

All Listed Sponsors
lead

Shandong Public Health Clinical Center

OTHER_GOV