Effect and Safety of Benzathine Penicillin Combined With Etanercept on Spondyloarthritis

PHASE4RecruitingINTERVENTIONAL
Enrollment

340

Participants

Timeline

Start Date

June 14, 2025

Primary Completion Date

March 1, 2027

Study Completion Date

July 31, 2027

Conditions
Spondyloarthritis (SpA)Ankylosing Spondylitis (AS)
Interventions
BIOLOGICAL

Etanercept

Prefilled syringe, 25mg of hypodermic injection, twice a week

DRUG

Benzathine Penicillin

Preparation of suspension with appropriate amount of sterilized water (4-5ml) for injection, 1.2 million units of intramuscular injection, once every two weeks

OTHER

Placebo

Preparation of suspension with appropriate amount of sterilized water (4-5ml) for injection, intramuscular injection, once every two weeks

Trial Locations (6)

230001

NOT_YET_RECRUITING

Anhui Provincial Hospital, Hefei

341000

NOT_YET_RECRUITING

Ganzhou People's Hospital, Ganzhou

400010

NOT_YET_RECRUITING

The Second Affiliated Hospital of Chongqing Medical University, Chongqing

510080

RECRUITING

Nan Fang Hospital, Southern Medical University, Guangzhou

510515

RECRUITING

Nan Fang Hospital, Southern Medical University, Guangzhou

010010

NOT_YET_RECRUITING

Inner Mongolia People's Hospital, Hohhot

All Listed Sponsors
lead

Nanfang Hospital, Southern Medical University

OTHER