Amniotic Suspension Allograft Injection for Knee Osteoarthritis

PHASE3RecruitingINTERVENTIONAL
Enrollment

160

Participants

Timeline

Start Date

October 21, 2024

Primary Completion Date

October 1, 2025

Study Completion Date

October 1, 2026

Conditions
KneeOsteoarthritis
Interventions
DRUG

ASA injection 40 mg group

Participants will receive intra-articular knee injections under ultrasound guidance with AMNIOGEN® 40mg (HCT Regenerative, New Taipei, Taiwan) diluted in 3.0 mL of sterile normal saline.

DRUG

ASA injection 20 mg group

Participants will receive intra-articular knee injections under ultrasound guidance with AMNIOGEN® 20mg (HCT Regenerative, New Taipei, Taiwan) diluted in 3.0 mL of sterile normal saline.

DRUG

HA injection group

Participants will receive intra-articular knee injections under ultrasound guidance with 3 ml of HyLink (SEIKAGAKU CORPORATION, Tokyo, Japan).

DRUG

Normal saline injection group

Participants will receive intra-articular knee injections under ultrasound guidance with 3 ml of sterile normal saline.

Trial Locations (2)

833

RECRUITING

Kaohsiung Chang Gung Memorial Hospital, Kaohsiung

RECRUITING

Department of Physical Medicine and Rehabilitation, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung City

All Listed Sponsors
lead

Chang Gung Memorial Hospital

OTHER