Characterization of the IFN-I Response in Subjects Who Experienced Severe or Mild Forms of COVID-19

NARecruitingINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

December 2, 2024

Primary Completion Date

June 30, 2026

Study Completion Date

June 30, 2027

Conditions
COVID-19
Interventions
OTHER

Biological Sampling

"The procedures specifically carried out for the study during a single visit are as follows:~* 1 nasopharyngeal swab for the baseline measurement of the nasal IFN-I score and to check for the presence of infection~* Blood sample collection in:~o1 yellow tube (5mL) for anti-interferon antibody measurement o1 PAXgene tube (2.5mL) for the baseline IFN score without stimulation o3 green heparin tubes (12mL) for performing immune-functional tests o2 large purple tubes (20mL) for biological collection (if the patient provides specific consent) oA total of 39.5mL of venous blood will be collected for the study during a single visit.~* Stool collection at home by the patient, to be sent by mail to the Biological Resource Center (CRB) of the Hospices Civils de Lyon (HCL) within 10 days after the visit.~* A food frequency questionnaire composed of 159 items measuring the frequency of consumption of foods and drinks over the past 12 months to complement the analysis of the gut microbiota."

Trial Locations (1)

69004

RECRUITING

Hospices Civils de Lyon - Hôpital de la Croix-Rousse, Lyon

All Listed Sponsors
lead

Hospices Civils de Lyon

OTHER