Research on Key Interventional Technologies for Controlling the Epidemic in High-prevalence Areas of Tuberculosis in Guangxi, China

NARecruitingINTERVENTIONAL
Enrollment

72,000

Participants

Timeline

Start Date

November 20, 2021

Primary Completion Date

January 31, 2025

Study Completion Date

April 30, 2025

Conditions
Tuberculosis (TB)
Interventions
DIAGNOSTIC_TEST

Active case finding

Villagers will be informed through public announcements and social workers. Before the campaign, social workers and village doctors will recruit participants and obtain consent through door-to-door visits. A mobile van equipped with an AI-assisted digital radiography (DR) machine and a refrigerator will visit villages on agreed dates. Participants will complete a TB symptom questionnaire and undergo DR screening. Those with TB symptoms or abnormal DR results will provide on-site sputum samples and collect additional morning and night samples. Trained staff will ensure proper collection and offer nebulizer support if needed. Samples will be transported daily to hospitals for testing using smear, culture, and GeneXpert. Participants with negative bacteriological results but abnormal findings will be referred for further clinical assessment.

Trial Locations (1)

530000

RECRUITING

Guangxi Zhuang Autonomous Region Center for Disease Control and Prevention, Nanning

All Listed Sponsors
collaborator

Guangxi Zhuang Autonomous Region Center for Disease Control and Prevention

UNKNOWN

lead

University of Toronto

OTHER