Clinical Study on the Risk of Left Atrial POP Ablation and Esophageal Injury Under Ultra-High Power and Related Influencing Parameters

NANot yet recruitingINTERVENTIONAL
Enrollment

120

Participants

Timeline

Start Date

November 28, 2024

Primary Completion Date

May 5, 2025

Study Completion Date

June 5, 2025

Conditions
Ultra-High Power Ablation,Safety of Atrial Fibrillation Ablation
Interventions
PROCEDURE

The ultra-high-power ablation group

The ultra-high-power ablation group will use the QDOT ablation catheter with a power of 90W, ablation points at site 3, inter-point distance maintained at 4-5mm, pressure maintained at 5-30g. The cold saline flow rate during ablation is 8ml/min, and the ablation device will adjust power and saline flow rate based on the electrode temperature at the tip of the QDOT ablation catheter. The target temperature is 60°C, and the cut-off temperature is 65°C, with an ablation endpoint of 4 seconds.

PROCEDURE

The high-power ablation group

The high-power ablation group will use the STSF ablation catheter with a power of 50W, ablation points at site 3, inter-point distance maintained at 4-5mm, pressure maintained at 5-30g, and a cold saline flow rate of 15ml/min during ablation. The ablation endpoint for the posterior wall of the left atrium is an Ablation Index (AI) value of 360-410, for the anterior wall 450-480, and for the bottom and top of the left atrium 420-450.

All Listed Sponsors
lead

The Third People's Hospital of Chengdu

OTHER

NCT06699368 - Clinical Study on the Risk of Left Atrial POP Ablation and Esophageal Injury Under Ultra-High Power and Related Influencing Parameters | Biotech Hunter | Biotech Hunter