Effect of Silver Diamine Fluoride Application on Oral Microbiome of Healthy Pediatric Patient

PHASE4RecruitingINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

November 1, 2023

Primary Completion Date

June 30, 2025

Study Completion Date

June 30, 2025

Conditions
Dental Caries
Interventions
DRUG

Silver diamine Fluoride 38%

"Intervention is the application of Silver diamine fluoride 38% to children Group in arm 1 (Arm 1): children will receive Silver diamine fluoride 38% application for 1 min to arrest primary teeth~SDF: (Silver diamine fluoride 38% is a material used for arresting caries lesions in primary and permanent teeth)~\- SDF Product generic name and information (E-SDF: it is a 1-step Technique) - The 38% SDF solution comprised a blend of silver, fluoride, and ammonia at a total concentration of 38%."

DRUG

Silver diamine fluoride- potassium iodide

"Intervention is the application of Silver diamine fluoride 38% + potassium iodide to children Group in arm 2 (Arm 2): children will receive Silver diamine fluoride 38% application for 1 min to arrest primary teeth, Followed by an second minute of potassium iodide solution application~\- SDF Product generic name and information (Riva-star: it is a 2-step Technique) 30-35% SDF solution (1st step) comprised a blend of silver, fluoride, and ammonia applied in combination with a second application of potassium iodide solution (2nd step)"

Trial Locations (1)

80209

RECRUITING

University Dental hospital of King Abdulaziz University, Jeddah

All Listed Sponsors
collaborator

King Fahd Medical Research Centre

OTHER

lead

King Abdulaziz University

OTHER