12
Participants
Start Date
September 30, 2025
Primary Completion Date
December 11, 2026
Study Completion Date
September 30, 2028
UF-KURE-BCMA CAR T-cells
"Experimental anti-BCMA CAR T-cells manufactured with a proprietary ultrafast process. Patients will receive a single dose of CAR T-cells at one of three potential doses:~* Dose -1: 3x10\^6 cells~* Dose 1: 10x10\^6 cells~* Dose 2: 15x10\^6 cells"
Cyclophosphamide
Patients will receive 3 days of intravenous (IV) cyclophosphamide 500 mg/m\^2 days -5 to -3 or -4 to -2 where day 0 is the day of CAR T-cell infusion.
Fludarabine
Patients will receive 3 days of IV fludarabine 30 mg/m2 days -5 to -3 or -4 to -2 where day 0 is the day of CAR T-cell infusion.
University Hospitals Cleveland Medical Center Seidman Cancer Center, Cleveland
David Wald
OTHER