Efficacy and Safety of Early Combined Therapy with PCSK9 Inhibitors and Statins in Acute Ischemic Stroke

PHASE4RecruitingINTERVENTIONAL
Enrollment

416

Participants

Timeline

Start Date

November 29, 2024

Primary Completion Date

June 1, 2027

Study Completion Date

December 1, 2027

Conditions
Acute Ischemic Stroke
Interventions
DRUG

PCSK9 inhibitors combined with atorvastatin/rosuvastatin

A single subcutaneous injection of 420 mg Iroceliumab upon admission, along with a standard dose of 20 mg Atorvastatin or 10 mg Rosuvastatin

DRUG

Atorvastatin/Rosuvastatin

Conventional Atorvastatin 20 mg / Rosuvastatin 10 mg

Trial Locations (2)

430030

RECRUITING

Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan

NOT_YET_RECRUITING

Tongji Hospital,Tongji Medical College, Huazhong University of Science and Technology, Wuhan

All Listed Sponsors
collaborator

The Third People's Hospital of Hubei Province

OTHER

collaborator

Hubei Shiyan People's Hospital

UNKNOWN

collaborator

Yichang Central People's Hospital

OTHER

collaborator

The Fifth Hospital of Wuhan

OTHER

collaborator

Shanghai Zhongshan Hospital

OTHER

collaborator

Renmin Hospital of Wuhan University

OTHER

collaborator

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

OTHER

collaborator

Wuhan Third Hospital

OTHER

collaborator

Taihe Hospital

OTHER

collaborator

Suizhou Hospital, Hubei University of Medicine

UNKNOWN

collaborator

Hubei Xinhua Hospital

OTHER

collaborator

Tianyou Hospital Affiliated to Wuhan University of Science and Technology

OTHER

collaborator

Minda Hospital Affiliated to Hubei University for Nationalities

UNKNOWN

lead

Xiang Luo

OTHER

NCT06696820 - Efficacy and Safety of Early Combined Therapy with PCSK9 Inhibitors and Statins in Acute Ischemic Stroke | Biotech Hunter | Biotech Hunter