Multi-center Prospective Clinical Study on Glucocorticoid Pulse Therapy for Graves' Ophthalmopathy (GO)

NAEnrolling by invitationINTERVENTIONAL
Enrollment

120

Participants

Timeline

Start Date

January 1, 2025

Primary Completion Date

June 30, 2026

Study Completion Date

December 31, 2026

Conditions
Graves Ophthalmopathy
Interventions
DRUG

High-Dose Methylprednisolone

Methylprednisolone 500mg, administered intravenously once daily for 3 consecutive days, repeated every 4 weeks for a total of 24 weeks, followed by a follow-up period.

DRUG

Low-Dose Methylprednisolone

Methylprednisolone is administered at a dose of 1mg/kg, given as an intravenous injection once daily for 3 consecutive days, repeated every 4 weeks for a total of 24 weeks, followed by a follow-up period.

Trial Locations (3)

200003

Shanghai Changzhen Hospital, Shanghai

200438

Shanghai Changhai Hospital, Shanghai

Unknown

Shanghai Longhua Hospital, Shanghai

All Listed Sponsors
lead

Zou Junjie

OTHER