Linaclotide for Colonoscopy Bowel Prep

PHASE1/PHASE2Not yet recruitingINTERVENTIONAL
Enrollment

10

Participants

Timeline

Start Date

September 1, 2025

Primary Completion Date

December 30, 2025

Study Completion Date

February 28, 2026

Conditions
Patients Scheduled for Colonoscopy
Interventions
DRUG

Use of Linaclotide as a single agent Colonoscopy prep

We plan to conduct a pilot study to determine the feasibility of a quality bowel preparation with two 290mg doses of Linaclotide (first dose given 36 hours before, and the other 8 hours prior to the procedure) along with 2 Liters of Gatorade (to prevent dehydration) given the day prior to the colonoscopy instead of the current standard 4 liters of PEG regimen. All study participants will be asked to consume a clear liquid diet for 24hours before the procedure.

Trial Locations (1)

32608

UF Health, Gainesville

All Listed Sponsors
lead

University of Florida

OTHER

NCT06692673 - Linaclotide for Colonoscopy Bowel Prep | Biotech Hunter | Biotech Hunter