10
Participants
Start Date
September 1, 2025
Primary Completion Date
December 30, 2025
Study Completion Date
February 28, 2026
Use of Linaclotide as a single agent Colonoscopy prep
We plan to conduct a pilot study to determine the feasibility of a quality bowel preparation with two 290mg doses of Linaclotide (first dose given 36 hours before, and the other 8 hours prior to the procedure) along with 2 Liters of Gatorade (to prevent dehydration) given the day prior to the colonoscopy instead of the current standard 4 liters of PEG regimen. All study participants will be asked to consume a clear liquid diet for 24hours before the procedure.
UF Health, Gainesville
University of Florida
OTHER