NCT06692361 - Assessment of the Efficacy and Safety of Fecal Microbiota Transplantation (FMT) in Patients with Major Depressive Disorder | Biotech Hunter

Enrollment

214

Participants

Timeline

Start Date

January 1, 2025

Primary Completion Date

June 30, 2026

Study Completion Date

December 31, 2026

Conditions

Major Depressive Disorder (MDD)Depression - Major Depressive Disorder

Interventions

BIOLOGICAL

FMT capsule

The experimental group will maintain escitalopram treatment and take 1.0 g of FMT capsules orally with breakfast every day for 4 weeks.

DRUG

Escitalopram (Lexapro)

Both the experimental group and the placebo group were treated with the maximum tolerated dose of escitalopram.

BIOLOGICAL

Corn Starch capsules

The placebo group will maintain escitalopram treatment and take corn starch capsules 1.0 g orally with breakfast every day for 4 weeks.

Trial Locations (7)

RECRUITING

Beijing Anding Hospital, Beijing

RECRUITING

Wuhu Fourth People's Hospital, Wuhu

RECRUITING

Shandong Daizhuang Hospital, Jining

NOT_YET_RECRUITING

Tianjin Anding Hospital, Tianjin

RECRUITING

The First Affiliated Hospital, Zhejiang University, Hangzhou

RECRUITING

West China Hospital Affiliated with sichuan University, Chengdu

RECRUITING

The First Hospital of Hebei Medical University, Shijiazhuang