An Open-Label, Pilot Clinical Trial To Test The Safety And Feasibility Of A Suspension of Freeze-dried Microbiota In Patients Undergoing Colon Resection

PHASE1RecruitingINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

February 18, 2025

Primary Completion Date

February 18, 2027

Study Completion Date

February 18, 2027

Conditions
Recurrent Clostridioides Difficile InfectionColonic Surgery
Interventions
DRUG

Orally administered preparation of fecal microbiota (MTP-101P)

As per standard of care, patients will receive MBP and OA the day prior to surgery as well as IV antibiotics at the time of surgery. MTP-101P will be given 48 hours after the administration of the dose of IV antibiotics to avoid the undesired bactericidal effects of antibiotics on the bacterial load from MTP-101P.

Trial Locations (1)

55414

RECRUITING

University of Minnesota, Minneapolis

All Listed Sponsors
lead

University of Minnesota

OTHER