Prophylactic Amnioinfusion for Prevention of Postpartum Hemorrhage

PHASE3Not yet recruitingINTERVENTIONAL
Enrollment

700

Participants

Timeline

Start Date

November 11, 2024

Primary Completion Date

November 11, 2026

Study Completion Date

May 1, 2027

Conditions
Postpartum Hemorrhage
Interventions
COMBINATION_PRODUCT

Saline delivered using an intrauterine pressure catheter (IUPC)

An intrauterine pressure catheter (IUPC) will be placed in participants after membrane rupture, or at 4 cm if membranes previously ruptured. A 300cc bolus of normal saline will be administered. A continuous rate of 100 cc/hr of normal saline will continue until delivery to prevent Postpartum Hemorrhage. If the IUPC is dislodged, it will be replaced by a trained clinician.

Trial Locations (1)

77030

The University of Texas Health Science Center at Houston, Houston

All Listed Sponsors
lead

The University of Texas Health Science Center, Houston

OTHER

NCT06691945 - Prophylactic Amnioinfusion for Prevention of Postpartum Hemorrhage | Biotech Hunter | Biotech Hunter