60
Participants
Start Date
March 28, 2025
Primary Completion Date
April 15, 2027
Study Completion Date
July 15, 2027
RELiZORB
RELiZORB (immobilized lipase) is a therapeutic device designed to enhance fat absorption in patients receiving enteral tube feedings. It works by hydrolyzing fats found in enteral formulas. RELiZORB is a single-use cartridge that connects in-line with enteral feeding sets. It contains lipase covalently bound to small polymer beads, forming a complex called iLipase, which remains within the cartridge. As the enteral formula passes through the cartridge, its fat content is hydrolyzed upon contact with iLipase. This process is especially beneficial for the absorption of long-chain polyunsaturated fatty acids, which require hydrolysis by pancreatic lipase for proper intestinal absorption. RELiZORB is compatible with a wide variety of commercially available enteral formulas.
RECRUITING
Massachusetts General Hospital, Boston
Collaborators (1)
Alcresta Therapeutics, Inc.
INDUSTRY
Massachusetts General Hospital
OTHER