Nicotine Pharmacokinetics and Subjective Effects of Oral Nicotine Products Relative to Smokeless Tobacco in Adult Users

Use of Test Product A in controlled use and ad libitum use sessions

Use of Test Product B in controlled use and ad libitum use sessions

Use of Test Product C in controlled use and ad libitum use sessions

Use of Test Product D in controlled use and ad libitum use sessions

Use of Test Product E in controlled use and ad libitum use sessions

Use of Reference Product F in controlled use and ad libitum use sessions. The subjects' Own Brand Moist Smokeless Tobacco (OBMST) reference products used in this study were commercially available and had been reported by the subjects as the brands they usually consume.