200
Participants
Start Date
July 7, 2025
Primary Completion Date
December 31, 2026
Study Completion Date
June 30, 2027
Photobiomodulation
Photomodulation (PBM) is a promising non-tissue penetrating (i.e. minimally invasive) approach for achieving tooth and soft tissue anesthesia/analgesia in dental patients. A patent pending near-infrared laser technology that aims to provide dental analgesia will be used for PBM. This intra-oral PBM device comes with a tip comprising of a series of photonic emitters with specific wavelengths that can go through the tooth structure and bone, blocking the nerve conduction like local anesthetics. Research has shown that one burst of light application (for about 20 second) can provide up to 15-20 minutes of pain relief. Based on existing research PBM does not present a serious risk to health, safety, or welfare of a subject.
Topical Benzocaine
Topical Benzocaine at injection site to reduce discomfort of local infiltration
Local Anesthesia
Local infiltration using local anesthetics with epinephrine
RECRUITING
University of Maryland School of Dentistry, Pediatric Clinics, Baltimore
University of Maryland, Baltimore
OTHER