A Study to Investigate Improvement in Pruritus of Lichen Simplex Chronicus With Dupilumab Injections Compared With Placebo in Male and Female Participants Aged at Least 18 Years (STYLE 2)

PHASE3RecruitingINTERVENTIONAL
Enrollment

136

Participants

Timeline

Start Date

November 25, 2024

Primary Completion Date

April 12, 2027

Study Completion Date

July 5, 2027

Conditions
Lichen Simplex Chronicus
Interventions
DRUG

Dupilumab

Pharmaceutical form: Solution for injection Route of administration: subcutaneous injection

DRUG

Placebo

Pharmaceutical form: Solution for injection Route of administration: subcutaneous injection

Trial Locations (64)

1427

RECRUITING

Investigational Site Number : 0320201, CABA

3570

RECRUITING

Investigational Site Number : 0560202, Alken

4000

RECRUITING

Investigational Site Number : 0320202, San Miguel de Tucumán

5000

RECRUITING

Investigational Site Number : 0320203, Córdoba

5900

ACTIVE_NOT_RECRUITING

Investigational Site Number : 3480202, Orosháza

7632

RECRUITING

Investigational Site Number : 3480201, Pécs

9990

RECRUITING

Investigational Site Number : 0560203, Maldegem

12200

RECRUITING

Investigational Site Number : 2760201, Berlin

14233

RECRUITING

Investigational Site Number : 3000203, Athens

15355

RECRUITING

Investigational Site Number : 4100202, Ansan-si

16121

RECRUITING

Investigational Site Number : 3000201, Athens

19114

RECRUITING

Clinical Research of Philadelphia- Site Number : 8400215, Philadelphia

20095

RECRUITING

Investigational Site Number : 2760205, Hamburg

21431

RECRUITING

Investigational Site Number : 4100203, Incheon

24105

RECRUITING

Investigational Site Number : 2760203, Kiel

27300

RECRUITING

Investigational Site Number : 7920202, Şahinbey

28034

RECRUITING

Investigational Site Number : 7240202, Madrid

28046

RECRUITING

Investigational Site Number : 7240201, Madrid

28223

RECRUITING

Investigational Site Number : 7240203, Pozuelo de Alarcón

30059

RECRUITING

Investigational Site Number : 1580203, Hsinchu

31217

RECRUITING

Skin Care Physicians of Georgia - Macon- Site Number : 8400236, Macon

33136

RECRUITING

University of Miami Miller School of Medicine- Site Number : 8400218, Miami

33305

RECRUITING

Investigational Site Number : 1580201, Taoyuan

33609

RECRUITING

TrueBlue Clinical Research- Site Number : 8400208, Tampa

34093

RECRUITING

Investigational Site Number : 7920201, Istanbul

34722

RECRUITING

Investigational Site Number : 7920203, Istanbul

40447

RECRUITING

Investigational Site Number : 1580202, Taichung

42104

RECRUITING

Equity Medical - Bowling Green- Site Number : 8400240, Bowling Green

44638

RECRUITING

Investigational Site Number : 4840201, Guadalajara

45500

RECRUITING

Investigational Site Number : 3000202, Ioannina

47201

RECRUITING

Southern Indiana Clinical Research Center- Site Number : 8400230, Columbus

60590

RECRUITING

Investigational Site Number : 2760202, Frankfurt am Main

64460

RECRUITING

Investigational Site Number : 4840202, Monterrey

77401

RECRUITING

Bellaire Dermatology Associates,- Site Number : 8400202, Bellaire

78229

RECRUITING

Progressive Clinical Research - San Antonio- Site Number : 8400206, San Antonio

78660

RECRUITING

Austin Institute for Clinical Research - Pflugerville- Site Number : 8400203, Pflugerville

80131

RECRUITING

Investigational Site Number : 3800201, Naples

92807

RECRUITING

Cosmetic Dermatology of Orange County- Site Number : 8400232, Anaheim

94538

RECRUITING

Center for Dermatology Clinical Research- Site Number : 8400226, Fremont

97070

RECRUITING

Investigational Site Number : 4840203, Yucatán

400038

RECRUITING

Investigational Site Number : 1560204, Chongqing

430022

RECRUITING

Investigational Site Number : 1560203, Wuhan

510091

RECRUITING

Investigational Site Number : 1560201, Guangzhou

510120

RECRUITING

Investigational Site Number : 1560202, Guangzhou

510515

RECRUITING

Investigational Site Number : 1560206, Guangzhou

7500504

RECRUITING

Investigational Site Number : 1520202, Santiago

8380465

RECRUITING

Investigational Site Number : 1520201, Santiago

02115

RECRUITING

Brigham & Women's Hospital- Site Number : 8400229, Boston

CP 1884

RECRUITING

Investigational Site Number : 0320204, Berazategui

T2W 4X9

RECRUITING

Investigational Site Number : 1240210, Calgary

T6W 0J5

RECRUITING

Investigational Site Number : 1240207, Edmonton

V3R 6A7

RECRUITING

Investigational Site Number : 1240201, Surrey

N6A 2C2

RECRUITING

Investigational Site Number : 1240205, London

L3P 1X3

RECRUITING

Investigational Site Number : 1240208, Markham

M2N 3A6

RECRUITING

Investigational Site Number : 1240209, Toronto

H4G 3E7

RECRUITING

Investigational Site Number : 1240203, Verdun

110 01

RECRUITING

Investigational Site Number : 2030201, Prague

160 00

RECRUITING

Investigational Site Number : 2030202, Prague

180 81

RECRUITING

Investigational Site Number : 2030203, Prague

00168

RECRUITING

Investigational Site Number : 3800202, Rome

03080

RECRUITING

Investigational Site Number : 4100201, Seoul

03312

RECRUITING

Investigational Site Number : 4100204, Seoul

03010

RECRUITING

Investigational Site Number : 7240204, Alicante

SO16 6YD

RECRUITING

Investigational Site Number : 8260201, Southampton

Sponsors

Lead Sponsor

All Listed Sponsors
collaborator

Regeneron Pharmaceuticals

INDUSTRY

lead

Sanofi

INDUSTRY

NCT06687980 - A Study to Investigate Improvement in Pruritus of Lichen Simplex Chronicus With Dupilumab Injections Compared With Placebo in Male and Female Participants Aged at Least 18 Years (STYLE 2) | Biotech Hunter | Biotech Hunter