PDO Based Drug Sensitive Test in R/M HNSCC

RecruitingOBSERVATIONAL
Enrollment

100

Participants

Timeline

Start Date

March 26, 2025

Primary Completion Date

November 11, 2026

Study Completion Date

November 11, 2028

Conditions
Head and Neck Squamous Cell CarcinomaPatient Derived OrganoidDrug Sensitive Test in Vitro
Interventions
OTHER

No intervention

The patients with R/M HNSCC would receive drug treatment according to the clinical guideline or doctor's experience, at the same time, tumor biopsy samples would be collected to establish PDO for drug sensitive test. But no intervention would be used based on the PDO drug sensitive test.

OTHER

No Intervention: Observational Cohort

The patients with R/M HNSCC would receive drug treatment according to the clinical guideline or doctor's experience, at the same time, tumor biopsy samples would be collected to establish PDO for drug sensitive test. But no intervention would be used based on the PDO drug sensitive test.

Trial Locations (2)

200040

ACTIVE_NOT_RECRUITING

Huashan Hospital, Fudan University, Shanghai

RECRUITING

Huashan Hospital, Fudan University, Shanghai

All Listed Sponsors
collaborator

Shanghai Cancer Hospital, China

OTHER

collaborator

Eye & ENT Hospital of Fudan University

OTHER

collaborator

Dongfang Hospital Affiliated to Tongji University

OTHER

collaborator

Shandong Cancer Hospital and Institute

OTHER

collaborator

Qilu Hospital of Shandong University

OTHER

collaborator

Shandong Provincial Hospital

OTHER_GOV

collaborator

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

OTHER

collaborator

Tongji Hospital

OTHER

collaborator

Hospital of Stomatology, Wuhan University

OTHER

collaborator

Second Affiliated Hospital, School of Medicine, Zhejiang University

OTHER

collaborator

First Affiliated Hospital of Zhejiang University

OTHER

collaborator

Sir Run Run Shaw Hospital

OTHER

collaborator

Zhejiang Cancer Hospital

OTHER

collaborator

Shanghai Zhongshan Hospital

OTHER

collaborator

Shanghai Huangpu District Central Hospital

UNKNOWN

lead

Huashan Hospital

OTHER